Neurology

Mouse studies suggest human neural stem cell (NSC)-derived extracellular vesicles could help treat stroke. In a mouse model of stroke, IV injection of NSC-derived extracellular vesicles decreased tissue loss and infarct size and increased somatosensory function compared with vehicle. In an aged mouse model of stroke, the vesicles decreased lesion volume and cerebral atrophy and increased coordination, motor skills and episodic memory. Next steps by ArunA Biomedical Inc. have included testing the vesicles in pig models of stroke (see “ArunA’s Exosome Entrance.” BioCentury Innovations (Jan. 4, 2018))...