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11:07 AM
Jul 10, 2017
 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Hepatitis C virus (HCV)

In vitro and cell culture studies identified analogs of the HCV NS3/4A protease complex inhibitor grazoprevir that could help treat drug-resistant HCV infections. Chemical synthesis and testing of grazoprevir analogs in vitro yielded five compounds that inhibited a drug-resistant...

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