ARTICLE | Distillery Therapeutics
Cancer
April 25, 2017 3:59 PM UTC
Cell culture studies suggest inhibiting CDK7 could help treat ovarian cancer. In five human ovarian cancer cell lines, a CDK7 inhibitor tool compound decreased proliferation compared with vehicle. In three of the cell lines, siRNA targeting CDK7 decreased proliferation compared with non-specific siRNA. Next steps include testing CDK7 inhibition in animal models of ovarian cancer...
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