BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Mycobacterium tuberculosis decaprenyl-phosphate N-acetylglucosaminephosphotransferase (rfe; wecA); M. tuberculosis phospho-N-acetylmuramoyl-pentap

October 13, 2016 7:00 AM UTC

In vitro and cell studies suggest muraymycin D1-based, dual inhibitors of Mycobacterium tuberculosis rfe and murX could help treat tuberculosis (TB). In in vitro enzymatic assays, the antibiotic muray...