Therapeutics: TCP1 containing ring complex (TRiC); T-complex 1 (TCP1; CCT1); chaperonin containing TCP1 subunit 3 (CCT3), CCT5; CCT7; CCT8; huntingtin (HTT)

Mouse and cell culture studies suggest promoting expression of TCP1, CCT3 and other TRiC subunits could help treat HD. In a synaptic formation assay utilizing co-cultured primary cortical and striatal...