12:00 AM
 | 
Sep 29, 2016
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: TCP1 containing ring complex (TRiC); T-complex 1 (TCP1; CCT1); chaperonin containing TCP1 subunit 3 (CCT3), CCT5; CCT7; CCT8; huntingtin (HTT)

Neurology

INDICATION: Huntington's disease (HD)

Mouse and cell culture studies suggest promoting expression of TCP1, CCT3 and other TRiC subunits could help treat HD. In a synaptic formation assay utilizing co-cultured primary cortical and striatal neurons from a mouse model of HD, treatment of the...

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