12:00 AM
 | 
Aug 25, 2016
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Peroxisome proliferation activated receptor γ coactivator 1-α (PPARGC1A; PGC-1a)

Cancer

INDICATION: Melanoma; viral infection

Mouse studies suggest enhancing PPARGC1A activity in T cells could help treat melanoma and chronic viral infections. In a mouse model of melanoma, adoptive transfer of tumor-targeting T cells induced to express PPARGC1A decreased tumor growth and...

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