BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Glutathione S-transferase π 1 (GSTP1); cereblon (CRBN)

July 28, 2016 7:00 AM UTC

Cell culture, in vitro and patient sample studies identified a promoter of CRBN-mediated GSTP1 degradation that could help treat AML. Screening of thalidomide analogs in human AML cell lines identifie...