12:00 AM
 | 
Jul 21, 2016
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2); MLL-AF9 fusion oncogene

Cancer

INDICATION: Acute myelogenous leukemia (AML)

Cell culture and mouse studies suggest inhibiting MTHFD2 could help treat AML. In human AML cell lines, shRNA targeting MTHFD2 decreased proliferation and colony...

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