BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Nuclear factor of activated T cells cytoplasmic calcineurin-dependent 1 (NFATc1); interleukin-10 (IL-10)

June 30, 2016 7:00 AM UTC

Mouse studies suggest inhibiting NFATc1 could help treat psoriasis. In a mouse model of psoriasis, knockout of NFATc1 in B cells increased IL-10 production in the spleen, decreased the number of CD4+ ...