12:00 AM
 | 
Jun 30, 2016
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Mycobacterium tuberculosis transmembrane transport protein 3 (MmpL3)

Infectious disease

INDICATION: Tuberculosis

In vitro, cell culture and mouse studies identified a carboxamide-based MmpL3 inhibitor that could help treat tuberculosis (TB). Chemical synthesis and testing in an M. tuberculosis-infected mammalian cell line of indole-carboxamide analogs identified a compound...

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