BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Mitochondrial complex 1 (MC-1)

June 9, 2016 7:00 AM UTC

In vitro, cell culture and mouse studies identified a metformin-based MC-1 inhibitor that could help treat pancreatic ductal adenocarcinoma (PDAC). Chemical synthesis and testing in a human PDAC cell ...