Therapeutics: Heat shock 70 kDa protein 5 (glucose-regulated protein, 78kDa) (HspA5; GRP78)

Cancer

INDICATION: Cancer; leukemia; melanoma

In vitro, cell culture and mouse studies identified a thiazole-based HspA5 inhibitor that could help treat drug-resistant melanoma and other cancers. Chemical synthesis and in vitro testing of thiazole

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