BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Sirtuin 6 (SIRT6); lin-28 homolog B (LIN28B)

May 19, 2016 7:00 AM UTC

Patient sample, cell culture and mouse studies suggest inhibiting LIN28B could help treat pancreatic ductal adenocarcinomas (PDACs) harboring loss-of-function SIRT6 mutations. In 30-40% of PDAC patien...