Therapeutics: β-catenin (CTNNB1); ubiquitin specific peptidase 6 (USP6)

Cancer

INDICATION: Cancer

Cell culture and mouse studies suggest inhibiting Wnt/CTNNB1 signaling could help treat nodular fasciitis, alveolar rhabdomyosarcoma and other USP6-overexpressing cancers. Screening of siRNA libraries in HEK cells and a

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