12:00 AM
Apr 28, 2016
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Microtubule-associated protein 1 light chain 3 β (MAP1LC3B; LC3B)


INDICATION: Cancer; prostate cancer

In vitro, cell culture and mouse studies identified a benzo[a]quinolizidine-based agonist of MAP1LC3B that could help treat prostate cancer. Chemical synthesis and in vitro testing of benzo[a]quinolizidine analogs identified a compound that inhibited...

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