Therapeutics: Methionine adenosyltransferase 2A (MAT2A); protein arginine methyltransferase 5 (PRMT5); RIO kinase 1 (RIOK1); methylthioadenosine phosphorylase (

Cancer

INDICATION: Colorectal cancer

Cell culture and mouse studies suggest inhibiting the MAT2A/PRMT5/RIOK1 axis could help

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