ARTICLE | Distillery Therapeutics
Therapeutics: κ opioid receptor (KOR; OPRK1); µ opioid receptor (MOR; OPRM1); opioid receptor δ1 (OPRD1; DOR); prepronociceptin (PNOC; NOP)
April 14, 2016 7:00 AM UTC
In vitro, mouse and rat studies identified two agonists of KOR, MOR and OPRD1 and antagonists of PNOC that could help treat neuropathic pain and diabetic neuropathy. Chemical synthesis of hybrids of a...