BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Tumor necrosis factor (TNF); adhesion G protein-coupled receptor E1 (ADGRE1)

March 10, 2016 8:00 AM UTC

Mouse studies suggest a bispecific macrophage-targeting antibody against TNF and ADGRE1 could help prevent liver damage. In a human TNF-expressing mouse model of chemical-induced fatal liver damage, p...