BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: ATPase Ca++ transporting plasma membrane 2 (ATP2B2; PMCA2); epidermal growth factor receptor 2 (HER2; EGFR2; ErbB2; neu)

February 11, 2016 8:00 AM UTC

Patient sample, cell culture and mouse studies suggest inhibiting ATP2B2 could help treat HER2-positive breast cancer. In 652 patients, high tumor levels of both ATP2B2 and HER2 correlated more closel...