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 | 
Oct 08, 2015
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Eukaryotic translation initiation factor 2 α kinase 4 (EIF2AK4; GCN2)

Autoimmune disease

INDICATION: Lupus

Cell culture and mouse studies suggest promoting EIF2AK4 activity could help treat lupus. In a mouse model of lupus, macrophage-specific knockout of EIF2AK4 increased numbers of spleen cells, spleen levels of...

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