ARTICLE | Distillery Therapeutics
Therapeutics: Claudin 5 (CLDN5); occludin (OCLN); β amyloid (Aβ)
October 1, 2015 7:00 AM UTC
In vitro and mouse studies suggest inhibiting CLDN5 and OCLN could help treat AD. In endothelial cell cultures, knockdown of both CLDN5 and OCLN increased paracellular diffusion of Aβ monomers across ...