BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Proprotein convertase subtilisin/kextin type 6 (PCSK6; PACE4); corin serine peptidase (CORIN)

September 17, 2015 7:00 AM UTC

In vitro and mouse studies suggest PCSK6 could activate the blood pressure regulator CORIN to help treat hypertension. In HEK cells, pharmacological or siRNA-mediated inhibition of PCSK6 decreased COR...