BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Hypoxia-inducible factor prolyl hydroxylase 2 (EGLN1; HIF-PH2; PHD2)

September 10, 2015 7:00 AM UTC

Mouse studies suggest PHD2 inhibition could help prevent or treat metastatic cancer. In a mouse model of breast cancer, systemic or tumor cell-specific PHD2 knockout decreased the number and size of l...