ARTICLE | Distillery Therapeutics
Therapeutics: ADAM metallopeptidase domain 10 (ADAM10); amyloid precursor protein (APP)
September 10, 2015 7:00 AM UTC
In vitro and mouse studies suggest inhibiting ADAM10 could help treat fragile X syndrome. Levels of soluble APPα, an ADAM10-mediated cleavage product of APP, were higher in lymphoblastoid cells from f...