12:00 AM
Aug 27, 2015
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Cyclooxygenase-2 (COX-2); 5-lipoxygenase (ALOX5; 5-LO)


INDICATION: Inflammation; pain

In vitro and mouse studies suggest an inhibitor of COX-2 and ALOX5 could treat pain and inflammation. Chemical synthesis of barbituric acid analogs followed by testing in COX-2 and ALOX5 assays identified...

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