BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Kruppel-like factor 4 (KLF4; EZF); galectin-3 (LGALS3)

July 30, 2015 7:00 AM UTC

Cell culture and mouse studies suggest inhibiting KLF4 could help treat atherosclerosis. In atherosclerotic plaques, phenotypic conversion of smooth muscle cells to macrophage-like LGALS3-positive cel...