Therapeutics: Activating transcription factor 4 (ATF4); heme oxygenase decycling 1 (HMOX1; HO-1; Hsp32)

Cell culture, mouse and patient sample studies suggest inhibiting ATF4 could help treat cancer. In patients with breast or sarcomal tumors, levels of ATF4 and the antioxidant protein HMOX1 were higher...