ARTICLE | Distillery Therapeutics
Therapeutics: Retinoid X receptor-α (RXRA; RXRα); tumor necrosis factor (TNF) α
April 23, 2015 7:00 AM UTC
In vitro and mouse studies suggest a nitrostyrene-based RXRα inhibitor could help treat cancer. A chemical screen of a small molecule library identified a nitrostyrene analog that bound RXRα with a Kd...