ARTICLE | Distillery Therapeutics
Therapeutics: Inhibitor of κ light gene enhancer in B cells kinase α (IKKα; IKBKA; IKK1; CHUK; NFKBIKA); IKKβ (IKBKB; IKK2; NRKBIKB)
April 23, 2015 7:00 AM UTC
In vitro and mouse studies suggest the natural product (+)-ainsliadimer A could help treat cancer. In vitro, (+)-ainsliadimer A covalently bound the cysteine 46 residue of IKKα and IKKβ (Ki = 30 nM) a...