ARTICLE | Distillery Therapeutics
Therapeutics: CC chemokine receptor 5 (CCR5; CD195); transportin 3 (TNPO3)
April 9, 2015 7:00 AM UTC
In vitro studies suggest an aptamer-siRNA conjugate that inhibits CCR5 and TNPO3 could help treat HIV infection. The conjugate consisted of an aptamer that bound CCR5 with a Kd of 113 nM fused to an s...