BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4; MEKKK4)

April 2, 2015 7:00 AM UTC

Mouse studies suggest MAP4K4 inhibition could help treat cancer and ophthalmic indications. In normal mice, knockout of MAP4K4 in endothelial cells decreased cell proliferation and vascular developmen...