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ARTICLE | Distillery Therapeutics

Therapeutics: Notum pectinacetylesterase homolog (NOTUM); wingless-type MMTV integration site (WNT) Patent and licensing status unavailable

March 5, 2015 8:00 AM UTC

In vitro and in vivo studies suggest NOTUM could help treat WNT-driven cancers. In fruit flies, overexpression of fly NOTUM suppressed the expression of a gene activated by high levels of WNT signalin...