BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Complement component 3a receptor 1 (C3AR1; C3AR); NF-κB; complement 3 (C3)

January 29, 2015 8:00 AM UTC

In vitro and mouse studies suggest antagonizing C3AR could help treat AD. Abnormal NF-κB activation is associated with AD. In co-cultures of mouse astrocytes and normal mouse hippocampal neurons, astr...