BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: T-cell immunoreceptor with Ig and ITIM domains (TIGIT)

January 22, 2015 8:00 AM UTC

Studies in human tissue samples and mice suggest combined blockade of the PD-L1 and TIGIT coinhibitory receptors could help treat cancer. In human tumor samples, TIGIT was up-regulated in tumor-infilt...