BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Filamin A (FLNA); regulator of calcineurin 1 (RCAN1; DSC1)

January 22, 2015 8:00 AM UTC

Rat studies suggest FLNA could help treat periventricular heterotopia (PH) caused by a deficiency in RCAN1. In rats, shRNA knockdown of RCAN1 in the brain decreased FLNA levels and neuronal migration ...