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Aug 16, 2017
 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: 3-D models

Self-assembling multicellular BBB spheroids could help screen compounds for BBB permeability. The spheroids self-assembled from co-cultures of primary human astrocytes, brain vascular pericytes and either brain microvascular endothelial cells or a human cerebral microvascular endothelial cell line, and consisted of an astrocyte core encased in an outer layer of brain endothelial cells and pericytes. The outer...

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