9:10 AM
 | 
Jun 07, 2017
 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Cell models

iPS cell-derived brain microvascular endothelial cells could serve as BBB models for HD or Allan-Herndon-Dudley syndrome. The cells were generated by co-culturing iPS cells derived from patients in endothelial cell-conditioned media with fibroblast growth factor 2 (FGF2) and all-trans retinoic acid and RNA sequencing of the cells showed high concordance in gene expression profiles between them and cultured...

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