9:11 AM
Mar 14, 2017
 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: Transgenics and knockouts

A CRISPR-based gene editing method of generating point mutations could be used to create animal models of genetic diseases. The method introduced cytosine-to-thymine (C-to-T) mutations into the DNA of mouse embryos utilizing a guide RNA (gRNA) to target the genomic site of interest and a three-part fusion protein consisting...

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