12:00 AM
Sep 15, 2016
 |  BC Innovations  |  Distillery Techniques

Techniques: Mice with midbrain neuron-specific knockout of LIM homeobox transcription factor 1 α (LMX1A; LMX1) and LMX1B as a model of Parkinson's disease (PD)

Disease models

TECHNOLOGY: Transgenics and knockouts

LMX1A/LMX1B-knockout mice could be useful for screening therapies to treat PD. In mice, knockout of LMX1A and LMX1B in midbrain dopaminergic neurons...

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