Techniques: Transgenic mouse models of human chromosome 9 open reading frame 72 (C9orf72)-mutant amyotrophic lateral sclerosis (ALS) or frontotemporal dementia

Disease models

TECHNOLOGY: Transgenics and knockouts

Transgenic mice expressing repeat expansions of GGGGCC in human C9orf72 could be used to screen therapies for ALS or FTD.

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