BioCentury
ARTICLE | Distillery Techniques

Techniques: Inhibiting chromatin assembly factor 1 subunit A (CHAF1A) or CHAF1B to enhance the speed of induced pluripotent stem (iPS) cell generation

January 28, 2016 8:00 AM UTC

Inhibiting CHAF1A or CHAF1B could speed the conversion of somatic cells to iPS cells for use in regenerative cell therapy. In mouse embryonic fibroblasts engineered to express four commonly used pluri...