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12:00 AM, Sep 08, 2000  |  BC Extra | Financial News

Vertex note offering and redemption

VRTX said it intends to offer $200 million of convertible subordinated notes due in 2007, plus a $30 million overallotment. The notes will be convertible into VRTX stock at a price to be determined. Separately,...
12:00 AM, Sep 08, 2000  |  BC Extra | Financial News

Compugen sells shoe

Computational genomics company CGEN raised $7.5 million through the sale of 750,000 shares at $10 authorized to cover overallotments in its August IPO. The sale brings to $57.5 million the total raised in the deal,...
12:00 AM, Sep 08, 2000  |  BC Extra | Financial News

Esperion sells shoe

ESPR, a developer of cardiovascular disease treatments, raised $8.1 million through the sale of 900,000 shares at $9 authorized to cover overallotments in its August IPO. The sale brings to $62.1 million the total raised...
12:00 AM, Sep 08, 2000  |  BC Extra | Clinical News

OGS reports 18-month OGT 918 data

Researchers presented 18-month data from 18 Gaucher disease patients receiving Oxford Glycosciences' Vevesca ( OGT 918) oral N-butyldeoxynojirimycin glucosyltransferase inhibitor under an extension protocol. The study showed a statistically significant reduction in liver and spleen...
12:00 AM, Sep 08, 2000  |  BC Extra | Clinical News

Zonagen Vasomax and Vasofem update

ZONA said it was notified by the FDA that a partial clinical hold in effect for the company's Vasomax and Vasofem compounds may be lifted through the successful completion of a mechanistic study of brown...
12:00 AM, Sep 08, 2000  |  BC Extra | Top Story

Amgen, Transkaryotic closing arguments

As expected, closing arguments were heard from representatives of AMGN and TKTX in their patent infringement suit related to TKTX's gene activated erythropoietin before Judge William Young of the U.S. District Court for the District...
12:00 AM, Sep 08, 2000  |  BC Extra | Company News

Amersham Pharmacia launches HTS products

Amersham Pharmacia (Little Chalfont, U.K.), the life sciences business of Nycomed Amersham (LSE:NAM; NYE), launched its two Gold Toolbox products, one for generic labeling and the other for fluorescence resonance energy transfer labeling. The products...
12:00 AM, Sep 07, 2000  |  BC Extra | Clinical News

Therion begins two Phase II trials

Under a CRADA, Therion ( Cambridge, Mass.) and the National Cancer Institute began two additional Phase II trials of Prostvac VF, a live recombinant vaccine consisting of a vaccinia virus vector encoding human prostate-specific antigen...
12:00 AM, Sep 07, 2000  |  BC Extra | Clinical News

Genzyme reports Phase III results

In an international placebo-controlled Phase III trial of 53 patients undergoing cardiopulmonary bypass surgery, recombinant human antithrombin III (rhATIII) significantly reduced the use of fresh frozen plasma (p=<0.001), the trial's primary end point. A total...
12:00 AM, Sep 07, 2000  |  BC Extra | Clinical News

Shire completes SLI 381 Phase III

Shire (LSE:SHP; SHPGY) said it completed Phase III studies of SLI 381, a once-daily formulation of its marketed Adderall mixed salts of a single-entity amphetamine, to treat Attention Deficit Hyperactivity Disorder (ADHD), and said that...

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