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10:48 AM, Jun 21, 2018  |  BC Extra | Politics & Policy

FDA scraps biosimilars draft guidance

In an effort to reduce the cost and increase the efficiency of biosimilars development, FDA Thursday withdrew draft guidance on statistical approaches for evaluating analytical similarities between a proposed biosimilar and its reference product. The...
7:14 AM, Jun 21, 2018  |  BC Extra | Financial News

Rhythm raises $151.4M in follow-on

Rhythm Pharmaceuticals Inc. (NASDAQ:RYTM) raised $151.4 million through the sale of 5.7 million shares at $26.42 in a follow-on underwritten by Morgan Stanley, BofA Merrill Lynch, Cowen and Needham. The price is an 8% discount...
9:46 PM, Jun 20, 2018  |  BC Extra | Financial News

Four companies in IPO quintet post first-day gains

Four of the five biopharmas that priced IPOs late Wednesday posted gains on Thursday. Cell therapy company Avrobio Inc. (NASDAQ:AVRO) had the biggest first-day bump, climbing $12.20 (64%) to $31.20, while three others posted double-digit...
4:00 PM, Jun 20, 2018  |  BC Extra | Company News

Gawande to head Amazon-Berkshire-Chase healthcare company

Amazon.com Inc. (NASDAQ:AMZN), Berkshire Hathaway Inc. (NYSE:BRK.A; NYSE:BRK.B) and JPMorgan Chase & Co. (NYSE:JPM) hired Atul Gawande as CEO of their new company focused on U.S. employee healthcare, effective July 9. His experience draws from...
3:54 PM, Jun 20, 2018  |  BC Extra | Preclinical News

Broad ErbB inhibition arrests KRAS mutant cancer

Multi-ErbB inhibitors may provide a treatment option for K-Ras (KRAS)-driven lung cancer where ErbB family member EGFR1-specific therapies have failed, according to two studies published in Science Translational Medicine on Wednesday. The findings suggest a way...
3:45 PM, Jun 20, 2018  |  BC Extra | Company News

Management tracks: Sanofi, NantKwest

Sanofi (Euronext:SAN; NYSE:SNY) hired Jean-Baptiste Chasseloup de Chatillon as EVP and CFO, effective Oct. 1. He was CFO and EVP at automotive company PSA Group (Euronext:UG). Natural killer cell company NantKwest Inc. (NASDAQ:NK) said Chief Accounting...
3:40 PM, Jun 20, 2018  |  BC Extra | Company News

Roche, Tesaro decline to comment on potential bid

Roche (SIX:ROG; OTCQX:RHHBY) and Tesaro Inc. (NASDAQ:TSRO) declined to comment on an Intereconomía report that said Roche is working with Citibank on a bid to acquire Tesaro. Intereconomía cited sources familiar with the matter. This month,...
3:18 PM, Jun 20, 2018  |  BC Extra | Preclinical News

TRPV4 could be new target for brain edema

University of Tokyo researchers and colleagues found inhibiting transient receptor potential vanilloid 4 (TRPV4; VRL2) could help treat brain edema caused by traumatic brain injury or stroke, according to a paper published in The Journal...
2:18 PM, Jun 20, 2018  |  BC Extra | Politics & Policy

Senate rejects clawback attempt

The Senate rejected a bill on Wednesday that would have rescinded more than $7 billion previously approved for the Children’s Health Insurance Program (CHIP). The original legislation proposed by the Trump administration, called the Spending...
1:13 PM, Jun 20, 2018  |  BC Extra | Financial News

ObsEva raises $73M on heels of linzagolix data

ObsEva S.A. (NASDAQ:OBSV) raised $73.1 million through the sale of 4.8 million shares at $15.39 in a follow-on underwritten by J.P. Morgan, Credit Suisse Securities (USA), Jefferies, Wedbush Securities and H.C. Wainwright. The price is...

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