6:56 AM
Sep 20, 2018
 |  BC Extra  |  Preclinical News

RNA-modifying enzyme loops mRNA to increase oncogene translation

Boston Children's Hospital researchers showed interaction between a translation factor and RNA-modifying enzyme could enhance oncogene translation by circularizing mRNA, suggesting that disrupting the protein-protein interaction could help treat cancer.

At least two companies -- Storm Therapeutics Ltd. (Cambridge, U.K.) and Accent Therapeutics Inc. (Lexington, Mass) -- have...

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