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ARTICLE | Preclinical News

Paper-based method for POC metabolite diagnosis

September 13, 2018 8:11 PM UTC

A metabolite detection method described in a Science paper published Thursday could provide clinicians with a paper-based point-of-care diagnostic that could potentially measure 42 metabolites implicated in a range of diseases. The method could improve diagnosis and management of multiple diseases for which POC analysis of the underlying metabolite is not available.

Researchers at the Max Planck Institute for Medical Research designed the method to measure the product -- NADPH -- of an oxidation reaction between a metabolite and its coenzyme...