UCSF study suggests stress response inhibitor could treat prostate cancer

A new study from University of California San Francisco researchers suggests that releasing the "brakes" on a tumor's stress regulation system by inhibiting eukaryotic translation initiation factor 2A (EIF2A) could help treat metastatic prostate cancer.

Aggressive cancers such as metastatic prostate cancer are characterized by increased protein synthesis to fuel growth. The energy-intensive expansive processes are in turn regulated by stress response systems to mitigate cellular resources...