3:12 PM
 | 
Mar 02, 2018
 |  BC Extra  |  Preclinical News

Engineered Cas9 could increase PAM targeting, DNA specificity

A study published in Nature showed that using protein evolution methods on Staphylococcus pyogenes Cas9 (CRISPR-associated protein 9) broadened protospacer adjacent motif (PAM) compatibility and increased DNA specificity, suggesting that the engineered enzyme could improve CRISPR-Cas9 genome editing.

Scientists from the Broad Institute...

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