BioCentury
ARTICLE | Preclinical News

Amino acid transporter linked to depression

July 11, 2017 3:46 PM UTC

In a paper published in The Journal of Neuroscience, scientists showed that reduction of solute carrier family 6 member 15 (SLC6A15), a neutral amino acid transporter, in the nucleus accumbens is linked to increased susceptibility to depression and stress. The team also showed that increasing SLC6A15 expression inhibited depression-like behavior in mice, suggesting that it could be targeted to treat the indication.

The paper's authors included researchers from University of Maryland, The George Washington University, Icahn School of Medicine at Mount Sinai, McGill University and the University of Texas at El Paso...