Lexicon, Praecis, Exelixis file IPOs

Lexicon (The Woodlands, Texas), which generates knockout mice, filed to raise up to $100 million. The offering will be underwritten by J.P. Morgan; Credit Suisse First Boston; Dain Rauscher Wessels; and Punk Ziegel.

Praecis ( Cambridge, Mass.) filed to raise up to $156.4 million in an offering to be underwritten by Salomon Smith Barney; CIBC World Markets; and Credit Suisse First Boston. Praecis' Abarelix Depot, a luteinizing hormone releasing hormone/gonadotropin releasing hormone antagonist, has completed Phase III testing to treat prostate cancer. The product is partnered with Amgen (AMGN) and Synthelabo (Paris, France). Praecis previously filed for an IPO in 1998. ...